Recombinant Topoisomerase I 抗体
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北京 101111
Quick Overview for Recombinant Topoisomerase I 抗体 (ABIN7828628)
抗原
See all Topoisomerase I (TOP1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant Topoisomerase I Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human Topoisomerase I fragment
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亚型
- IgG, kappa
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anti-Topoisomerase (DNA) I (TOP1) (AA 692-765) antibody
TOP1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1A1 unconjugated
anti-Topoisomerase (DNA) I (TOP1) antibodyTOP1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Topoisomerase (DNA) I (TOP1) antibodyTOP1 适用: 人 WB, ELISA, IHC, IP, FACS 宿主: 兔 Monoclonal 6D8 unconjugated Recombinant Antibody
anti-Topoisomerase (DNA) I (TOP1) antibodyTOP1 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) I (TOP1) (AA 1-100) antibodyTOP1 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) I (TOP1) (Internal Region) antibodyTOP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) I (TOP1) antibodyTOP1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB7195 unconjugated
anti-Topoisomerase (DNA) I (TOP1) antibodyTOP1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB2060 unconjugated Recombinant Antibody
anti-Topoisomerase (DNA) I (TOP1) (N-Term) antibodyTOP1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 1291CT875-142-166 unconjugated
anti-Topoisomerase (DNA) I (TOP1) antibodyTOP1 适用: 人, 大鼠 WB, FACS 宿主: 小鼠 Monoclonal 1C6 unconjugated
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应用备注
- WB 1:500-1:2000,IHC 1:100-1:500,IF 1:50,FCM 1:50-1:100,IP 1:25-1:50
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))
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别名
- Topoisomerase I
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背景
- TOP,TOP1,TOPI,DNA topoisomerases play essential roles in many DNA metabolic processes including DNA repair. Topoisomerases can introduce DNA damage upon exposure to drugs that stabilize the covalent protein-DNA intermediate of the topoisomerase reaction. Lesions in DNA are also able to trap topoisomerase-DNA intermediates. DNA topoisomerase I (Top1) catalyzes the relaxation of supercoiled DNA by a mechanism of transient DNA strand cleavage characterized by the formation of a phosphotyrosyl bond between the DNA end and active site tyrosine. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 91 kDa
Observed MW: 108 kDa The actual band is not consistent with the expectation.
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UniProt
- P11387
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途径
- Caspase Cascade in Apoptosis, Stem Cell Maintenance
抗原
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