Recombinant TREX1 抗体
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北京 101111
Quick Overview for Recombinant TREX1 抗体 (ABIN7828620)
抗原
See all TREX1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant TREX1 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human TREX1 fragment
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亚型
- IgG, kappa
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anti-three Prime Repair Exonuclease 1 (TREX1) (AA 1-369) antibody
TREX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-three Prime Repair Exonuclease 1 (TREX1) (AA 1-270) antibodyTREX1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-three Prime Repair Exonuclease 1 (TREX1) (AA 1-270) antibodyTREX1 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-three Prime Repair Exonuclease 1 (TREX1) antibodyKD Validated TREX1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB2440 unconjugated Recombinant Antibody
anti-three Prime Repair Exonuclease 1 (TREX1) (AA 1-304) antibodyTREX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-three Prime Repair Exonuclease 1 (TREX1) (AA 1-100) antibodyTREX1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F10 unconjugated
anti-three Prime Repair Exonuclease 1 (TREX1) (AA 6-369) antibodyTREX1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-three Prime Repair Exonuclease 1 (TREX1) antibodyTREX1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-three Prime Repair Exonuclease 1 (TREX1) (AA 1-100) antibodyTREX1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B1 unconjugated
anti-three Prime Repair Exonuclease 1 (TREX1) (AA 1-369) antibodyTREX1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB 1:1000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- TREX1 (three Prime Repair Exonuclease 1 (TREX1))
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别名
- TREX1
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背景
- TREX,Trex1,TREX1 is a broadly expressed 3' to 5' exonuclease that acts on single-stranded DNA (ssDNA) to negatively regulate the interferon-stimulatory DNA (ISD) response. In humans, there are three TREX1 isoforms generated through alternative splicing with predicted molecular weights of 32, 33, and 39 kDa. The transcript for the 33 kDa isoform is the most abundant. Mice deficient in TREX1 accumulate intracellular ssDNA, which triggers the ISD response and eventually lethal autoimmunity. Mutations in TREX1 are associated with autoimmune diseases including Aicardi-Goutieres syndrome and systemic lupus erythematosus. In addition, TREX1 prevents the cell-intrinsic innate immune response to human immunodeficiency virus (HIV) by digesting excess HIV DNA that would normally trigger induction of type I interferon. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 34 kDa
Observed MW: 34 kDa
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UniProt
- Q91XB0
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途径
- Apoptosis
抗原
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