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Recombinant SUV39H1 抗体

The 兔 单克隆 anti-SUV39H1 antibody (Clone A372) (ABIN7828596) specifically detects SUV39H1 in WB. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7828596
发货至: 中国
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Quick Overview for Recombinant SUV39H1 抗体 (ABIN7828596)

抗原

See all SUV39H1 抗体
SUV39H1 (Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1))

抗体类型

Recombinant Antibody

适用

  • 58
  • 18
  • 6
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  • 5
  • 5
  • 5
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  • 2
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  • 2
  • 1
人, 小鼠

宿主

  • 50
  • 8

克隆类型

  • 50
  • 8
单克隆

标记

  • 25
  • 6
  • 5
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SUV39H1 antibody is un-conjugated

应用范围

  • 36
  • 31
  • 13
  • 13
  • 13
  • 6
  • 6
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB)

克隆位点

A372
  • 原理

    Recombinant SUV39H1 Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human SUV39H1 fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:500-1:1000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    SUV39H1 (Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1))

    别名

    SUV39H1

    背景

    SUV39H1,H3-K9-HMTase 1,KMT1A,MG44,SUV39H,H3-K9-HMTase1,Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. Also weakly methylates histone H1 (in vitro). H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as repression of MYOD1-stimulated differentiation, regulation of the control switch for exiting the cell cycle and entering differentiation, repression by the PML-RARA fusion protein, BMP-induced repression, repression of switch recombination to IgA and regulation of telomere length. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 48 kDa

    Observed MW: 48 kDa

    UniProt

    O43463
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