SUV39H1 抗体 (N-Term)
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北京 101111
Quick Overview for SUV39H1 抗体 (N-Term) (ABIN2779665)
抗原
See all SUV39H1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- SUV39H1 Antibody - N-terminal region
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序列
- RHLDPSLANY LVQKAKQRRA LRRWEQELNA KRSHLGRITV ENEVDLDGPP
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against SUV39H1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SUV39H1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32471-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- SUV39H1 (Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1))
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别名
- SUV39H1
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背景
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Background Information: SUV39H1, a human homolog of the Drosophila position effect variegation modifier Su(var)3-9 and of the S. pombe silencing factor clr4, encodes a heterochromatic protein that transiently accumulates at centromeric positions during mitosis. This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gene Name: Suppressor of variegation 3-9 homolog 1 (Drosophila)
Alternative Symbols: MG44, KMT1A, SUV39H, H3-K9-HMTase 1
Protein Name: Histone-lysine N-methyltransferase SUV39H1
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分子量
- 48kDa
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基因ID
- 6839
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NCBI登录号
- NP_003164
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UniProt
- O43463
抗原
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