Recombinant SP1 抗体
Our Local Distributor
北京 101111
Quick Overview for Recombinant SP1 抗体 (ABIN7828578)
抗原
See all SP1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Recombinant SP1 Monoclonal Antibody
-
纯化方法
- Protein A purified
-
免疫原
- Recombinant human SP1 fragment
-
亚型
- IgG, kappa
-
-
-
-
应用备注
- WB 1:1000,IHC 1:50
-
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
-
有效期
- 12 months
-
-
- SP1 (Sp1 Transcription Factor (SP1))
-
别名
- SP1
-
背景
- Specificity protein,Transcription factor Sp,SP1,SP 1,Sp1 transcription factor,Specificity protein 1,Transcription factor Sp1,TSFP 1,TSFP1,Specificity protein 1 (SP1) is a ubiquitously expressed transcription factor belonging to the family of C2H2-type zinc finger containing DNA-binding proteins. SP1 binds GC-rich motifs with high affinity and regulates the expression of numerous mammalian genes. It interacts with many other transcription factors, such as c-Myc, EGR1, and Stat1, and with basal transcription machinery components. SP1 interacts with chromatin-modifying factors, such as histone deacetylases (HDACs) and p300 in chromatin remodeling. Transcriptional activity and stability of SP1 are regulated by post-translational modification, including phosphorylation, acetylation, ubiquitination, and glycosylation. Glycosylation of SP1 following insulin treatment leads to increased nuclear localization, while glucagon treatment increases cytoplasmic SP1 levels. Investigators have found high levels of SP1 in patients with Alzheimer's disease. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
-
分子量
-
Calculated MW: 81 kDa
Observed MW: 100 kDa The actual band is not consistent with the expectation.
-
UniProt
- P08047
-
途径
- Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
抗原
-