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Recombinant SP1 抗体

The 兔 单克隆 anti-SP1 antibody (Clone A682) (ABIN7828578) specifically detects SP1 in WB 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7828578
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant SP1 抗体 (ABIN7828578)

抗原

See all SP1 抗体
SP1 (Sp1 Transcription Factor (SP1))

抗体类型

Recombinant Antibody

适用

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人, 小鼠, 大鼠

宿主

  • 111
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克隆类型

  • 83
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单克隆

标记

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This SP1 antibody is un-conjugated

应用范围

  • 113
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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

A682
  • 原理

    Recombinant SP1 Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human SP1 fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:1000,IHC 1:50

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    SP1 (Sp1 Transcription Factor (SP1))

    别名

    SP1

    背景

    Specificity protein,Transcription factor Sp,SP1,SP 1,Sp1 transcription factor,Specificity protein 1,Transcription factor Sp1,TSFP 1,TSFP1,Specificity protein 1 (SP1) is a ubiquitously expressed transcription factor belonging to the family of C2H2-type zinc finger containing DNA-binding proteins. SP1 binds GC-rich motifs with high affinity and regulates the expression of numerous mammalian genes. It interacts with many other transcription factors, such as c-Myc, EGR1, and Stat1, and with basal transcription machinery components. SP1 interacts with chromatin-modifying factors, such as histone deacetylases (HDACs) and p300 in chromatin remodeling. Transcriptional activity and stability of SP1 are regulated by post-translational modification, including phosphorylation, acetylation, ubiquitination, and glycosylation. Glycosylation of SP1 following insulin treatment leads to increased nuclear localization, while glucagon treatment increases cytoplasmic SP1 levels. Investigators have found high levels of SP1 in patients with Alzheimer's disease. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 81 kDa

    Observed MW: 100 kDa The actual band is not consistent with the expectation.

    UniProt

    P08047

    途径

    Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
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