Recombinant RAB8A 抗体
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北京 101111
Quick Overview for Recombinant RAB8A 抗体 (ABIN7828515)
抗原
See all RAB8A 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant Rab8A Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human Rab8A fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:1000-1:2000,IHC 1:50-1:100
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))
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别名
- Rab8A
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背景
- RAB,RAB8A,MEL,RAB8,AA409338,Mel transforming oncogene,Mel transforming oncogene (derived from cell line NK14),Mel transforming oncogene (derived from cell line NK14) RAB8 homolog,Mel transforming oncogene (RAB8 homolog),MGC124948,Oncogene c mel,Oncogene c-mel,RAB8A member RAS oncogene family,Ras associated protein RAB8,Ras related protein Rab 8A,Ras-related protein Rab-8A,The Rab8 GTPase is a member of the Ras superfamily that functions in protein transport and membrane restructuring. RAB8 has two isoforms, RAB8A and RAB8B, that share 40 % amino acid identity in the C-terminal variable region. RAB8 activity is regulated by specific guanine nucleotide exchange factors (GEFs), that mediate GTP loading, and GTPase activating proteins (GAPs) that convert them into the inactive GDP-bound form. RAB8 participates in recycling of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors to the dendritic spine surface as well as in the intracellular transport of the metabotropic glutamate receptor type 1 in neuronal cells. Rab8 is activated at the base of the cilium by its guanine nucleotide exchanger Rabin8. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 24 kDa
Observed MW: 24 kDa
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UniProt
- P61006
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途径
- M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interactome
抗原
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