Recombinant PTPN12 抗体
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北京 101111
Quick Overview for Recombinant PTPN12 抗体 (ABIN7828502)
抗原
See all PTPN12 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant PTPN12 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human PTPN12 fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:1000-1:5000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))
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别名
- PTPN12
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背景
- PTPG,PTPN,PTPG1,PTP-PEST,PTPN12,PTP-PEST,Protein tyrosine phosphatase G1,Protein tyrosine phosphatase non receptor type 12,Protein-tyrosine phosphatase G1,PTN12,PTP PEST,Tyrosine protein phosphatase non receptor type 12,Tyrosine-protein phosphatase non-receptor type 12,PTPN12 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 88 kDa
Observed MW: 120 kDa The actual band is not consistent with the expectation.
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UniProt
- Q05209
抗原
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