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PTPN12 抗体

PTPN12 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7075292
发货至: 中国
  • 抗原 See all PTPN12 抗体
    PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))
    适用
    • 49
    • 9
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 43
    • 6
    克隆类型
    • 44
    • 5
    多克隆
    标记
    • 31
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PTPN12 antibody is un-conjugated
    应用范围
    • 43
    • 14
    • 14
    • 13
    • 10
    • 9
    • 8
    • 5
    • 4
    • 3
    • 3
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    人, 大鼠
    纯化方法
    Affinity purification
    免疫原
    KLH conjugated Synthetic peptide corresponding to Mouse PTPN12
  • 应用备注
    WB (H,M,R) 1: 500-1: 800, IHC/IF (H,M,R) 1:1000-1:3000/1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))
    别名
    PTPN12 (PTPN12 产品)
    别名
    PTP-PEST antibody, PTPG1 antibody, P19-PTP antibody, PTP-P19 antibody, Ptpg1 antibody, RKPTP antibody, protein tyrosine phosphatase, non-receptor type 12 antibody, PTPN12 antibody, Ptpn12 antibody
    背景
    The PTPN12 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. The PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion. This suggests it has a regulatory role in controlling cell shape and mobility.
    分子量
    110 kDa
    基因ID
    19248
    NCBI登录号
    NP_035333
    UniProt
    P35831
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