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Recombinant PRMT5 抗体

The 兔 单克隆 anti-PRMT5 antibody is suitable to detect PRMT5 in samples from 人. It has been validated for WB, IHC 和 IP.
产品编号 ABIN7828493
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant PRMT5 抗体 (ABIN7828493)

抗原

See all PRMT5 抗体
PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This PRMT5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

克隆位点

A338
  • 原理

    Recombinant PRMT5 Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human PRMT5 fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:2000-1:10000,IHC 1:50-1:100,IP 1:25-1:50

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

    别名

    PRMT5

    背景

    IBP,JBP,SKB,PRMT,HRMT1L,HRMT1L5,IBP72,JBP1,SKB1,SKB1Hs,PRMT5,72 kDa ICln binding protein,72 kDa ICln-binding protein,ANM5,Histone synthetic lethal 7,Histone-arginine N-methyltransferase PRMT5,HMT1 hnRNP methyltransferase like 5,homolog of,Jak-binding protein 1,JBP 1,PRMT 5,Protein arginine methyltransferase 5,Protein arginine N methyltransferase 5,Protein arginine N methyltransferase 5 N terminally processed,Protein arginine N-methyltransferase 5,S. cerevisiae,S. POMBE,S. POMBE HOMOLOG OF,SHK1 KINASE BINDING PROTEIN 1,Shk1 kinase binding protein 1 homolog,Shk1 kinase/binding protein 1,Shk1 kinase-binding protein 1 homolog,SKB 1,SKB1 homolog,SKB1: SKB1 homolog (S. pombe),Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H and may regulate its transcriptional elongation properties. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation. Methylates histone H2A and H4 'Arg-3' during germ cell development. Methylates histone H3 'Arg-8', which may repress transcription. Methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 73 kDa

    Observed MW: 70 kDa The actual band is not consistent with the expectation.

    UniProt

    O14744

    途径

    Chromatin Binding, Regulation of Muscle Cell Differentiation, Ribonucleoprotein Complex Subunit Organization, Skeletal Muscle Fiber Development
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