Recombinant ALIX 抗体
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北京 101111
Quick Overview for Recombinant ALIX 抗体 (ABIN7828485)
抗原
See all ALIX (PDCD6IP) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant ALIX Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human ALIX fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:2000-1:10000,IHC 1:100-1:500,IP 1:25-1:50
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
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别名
- ALIX
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背景
- AIP,DRIP,KIAA,PDCD6IP,AIP1,ALIX,DRIP4,HP95,KIAA1375,Programmed cell death 6-interacting protein (PDCD6IP), plays an important role in the endosomal sorting complexes required for transport (ESCRT) pathway in the abscission stage of cytokinesis and apoptosis. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the protein binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. It also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this protein and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 96 kDa
Observed MW: 90/100 kDa The actual band is not consistent with the expectation.
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UniProt
- Q8WUM4
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途径
- p53 Pathway, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation
抗原
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