Recombinant PNKP 抗体
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北京 101111
Quick Overview for Recombinant PNKP 抗体 (ABIN7828469)
抗原
See all PNKP 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant PNKP Monoclonal Antibody
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纯化方法
- Protein A purified
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亚型
- IgG, kappa
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应用备注
- WB 1:2000,IHC 1:100
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))
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别名
- PNKP
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背景
- AOA,EIEE,PNKP,AOA4,EIEE10,MCSZ,PNK,PNK (polynucleotide kinase) is a DNA repair enzyme that participates in single strand break repair and non-homologous end rejoining (NHEJ) for double strand breaks. PNK possesses a 5'-DNA kinase activity and a 3'-DNA phosphatase activity. It has three domains, a C terminal kinase domain, a central phosphatase domain, and an N-terminal forkhead associated (FHA) domain that is responsible for protein protein interactions. Reduction in expression of PNK by RNAi sensitizes cells to ionizing radiation and topoisomerase I inhibitors. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 57 kDa
Observed MW: 60 kDa The actual band is not consistent with the expectation.
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UniProt
- Q96T60
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途径
- DNA Damage Repair, Nucleotide Phosphorylation
抗原
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