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Recombinant PNKP 抗体

The 兔 单克隆 anti-PNKP antibody is suitable to detect PNKP in samples from 人. It has been validated for WB 和 IHC.
产品编号 ABIN7828469
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant PNKP 抗体 (ABIN7828469)

抗原

See all PNKP 抗体
PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This PNKP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

A752
  • 原理

    Recombinant PNKP Monoclonal Antibody

    纯化方法

    Protein A purified

    亚型

    IgG, kappa
  • 应用备注

    WB 1:2000,IHC 1:100

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

    别名

    PNKP

    背景

    AOA,EIEE,PNKP,AOA4,EIEE10,MCSZ,PNK,PNK (polynucleotide kinase) is a DNA repair enzyme that participates in single strand break repair and non-homologous end rejoining (NHEJ) for double strand breaks. PNK possesses a 5'-DNA kinase activity and a 3'-DNA phosphatase activity. It has three domains, a C terminal kinase domain, a central phosphatase domain, and an N-terminal forkhead associated (FHA) domain that is responsible for protein protein interactions. Reduction in expression of PNK by RNAi sensitizes cells to ionizing radiation and topoisomerase I inhibitors. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 57 kDa

    Observed MW: 60 kDa The actual band is not consistent with the expectation.

    UniProt

    Q96T60

    途径

    DNA Damage Repair, Nucleotide Phosphorylation
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