Recombinant c-MYC 抗体 (pSer62)
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Quick Overview for Recombinant c-MYC 抗体 (pSer62) (ABIN7828408)
抗原
See all c-MYC (MYC) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pSer62
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原理
- Recombinant Phospho-c-Myc (Ser62) Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- phosphorylated human c-Myc (Ser62) peptide
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亚型
- IgG, kappa
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应用备注
- WB 1:1000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
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别名
- c-Myc
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背景
- BHLHe,MYC BHLHE,MRTL,MYCC,bHLHe39,c-Myc,MYC,MYC BHLHE39,AU016757,Avian myelocytomatosis viral oncogene homolog,c Myc,Class E basic helix-loop-helix protein 39,Myc protein,Myc proto oncogene protein,Myc proto-oncogene protein,Myc2,myc-related translation/localization regulatory factor,Myelocytomatosis oncogene,Niard,Nird,Oncogene Myc,OTTHUMP00000158589,Proto-oncogene c-Myc,Protooncogene homologous to myelocytomatosis virus,RNCMYC,Transcription factor p64,Transcriptional regulator Myc-A,V-Myc avian myelocytomatosis viral oncogene homolog,v-myc myelocytomatosis viral oncogene homolog (avian),V-myc myelocytomatosis viral oncogene homolog(avian),Myc, also known as c-Myc, together with l-Myc and n-Myc, belongs to the Myc family of transcription factors. Myc has a basic helix-loop-helix leucine zipper domain and through heterodimerization can bind and regulate the transcriptional activity of genes. It is a key player in the regulation of cell growth and cell cycle progression and acts as a proto-oncogene. Myc localizes to the nucleus but can also be present in the cytoplasm of certain cancer types. Myc is ubiquitously expressed in almost all cell types and its expression positively correlates with tissue proliferative capacity. Myc is also expressed during embryogenesis. Myc is upregulated in many cancer types, especially in aggressive, poorly differentiated tumors. Mutations in the MYC gene and breakpoint translocations within the MYC gene cause Burkitt lymphoma. In addition, Myc is subject to various post-translational modifications, including phosphorylation, acetylation, and ubiquitinylation. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 49 kDa
Observed MW: 55 kDa The actual band is not consistent with the expectation.
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UniProt
- P01106
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途径
- p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
抗原
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