Recombinant MCM7 抗体
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北京 101111
Quick Overview for Recombinant MCM7 抗体 (ABIN7828393)
抗原
See all MCM7 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant MCM7 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human MCM7 fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:2000-1:10000,IHC 1:50-1:100,IF 1:50,FCM 1:50-1:100
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
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别名
- MCM7
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背景
- CDC,PNAS,P1CDC,PPP1R,P1.1-MCM,MCM,MCM7,CDC47,MCM2,P1.1-MCM3,P1CDC47,P85MCM,PNAS146,PPP1R104,formerly,homolog of,regulatory subunit 104,S. cerevisiae,CDABP0042,CDC 47,CDC47 homolog,DNA replication licensing factor MCM7,Homolog of S. cerevisiae Cdc47,MCM 2,MCM 7,MCM7 minichromosome maintenance deficient 7,MCM7_HUMAN,Minichromosome maintainence,Minichromosome Maintainence 7,Minichromosome maintenance complex component 7,Minichromosome maintenance deficient 7,Minichromosome maintenance protein 7,P1.1 MCM3,PNAS 146,Protein phosphatase 1,DNA replication licensing factor MCM7 acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for once per cell cycle DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. MCM7 is also required for S-phase checkpoint activation upon UV-induced damage. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 81 kDa
Observed MW: 81 kDa
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UniProt
- P33993
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途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
抗原
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