Recombinant JMJD2D 抗体
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北京 101111
Quick Overview for Recombinant JMJD2D 抗体 (ABIN7828364)
抗原
See all JMJD2D (KDM4D) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant JMJD2D Monoclonal Antibody
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纯化方法
- Protein A purified
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亚型
- IgG, kappa
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anti-Lysine (K)-Specific Demethylase 4D (KDM4D) antibody
KDM4D 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (C-Term) antibodyKDM4D 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (AA 337-499) antibodyKDM4D 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (N-Term) antibodyKDM4D 适用: 人, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (AA 1-523) antibodyKDM4D 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (C-Term) antibodyKDM4D 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (AA 434-483) antibodyKDM4D 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (AA 484-516) antibodyKDM4D 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
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别名
- JMJD2D
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背景
- JHD3D,JmjC domain-containing histone demethylation protein 3D,Jumonji domain-containing protein 2D,Lysine-specific demethylase 4D,JHDM3D,JMJD2D,KDM4D,JMJD2D (KDM4D) is a histone demethylase located in the nucleus that specifically demethylates Lysine 9 of Histone H3, thereby playing a central role in the histone code. JMJD2D (KDM4D) demethylates both di- and trimethylated histone H3 Lys 9, while it has no activity on monomethylated residues. The demethylation reaction of the Lys residue generates formaldehyde and succinate as a by product. In addition, JMJD2D forms a complex with the ligand-bound form of the Androgen Receptor (AR) and, through this interaction, activates AR expression. Overexpression of AR is associated with prostate cancer, suggesting that, via its ability to upregulate AR, JMJD2D (KDM4D) may be involved in carcinogenesis. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 59 kDa
Observed MW: 65 kDa The actual band is not consistent with the expectation.
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UniProt
- Q6B0I6
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途径
- Warburg Effect
抗原
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