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- 抗原 See all JMJD2D (KDM4D) 抗体
- JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
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抗原表位
- AA 484-516
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This JMJD2D antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB)
- 纯化方法
- Purified
- 免疫原
- A portion of amino acids 484-516 from the human protein was used as the immunogen for this JMJD2D antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product KDM4D Primary Antibody
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anti-Lysine (K)-Specific Demethylase 4D (KDM4D) antibody
KDM4D 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (C-Term) antibodyKDM4D 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (AA 337-499) antibodyKDM4D 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (AA 1-523) antibodyKDM4D 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (N-Term) antibodyKDM4D 适用: 人, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (AA 460-520) antibodyKDM4D 适用: 人, 猴, 灵长类 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (C-Term) antibodyKDM4D 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (AA 434-483) antibodyKDM4D 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Titration of the JMJD2D antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the JMJD2D antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
- 别名
- JMJD2D (KDM4D) (KDM4D 产品)
- 别名
- JMJD2D antibody, 4932416A15 antibody, Jmjd2d antibody, KDM4D antibody, lysine demethylase 4D antibody, lysine-specific demethylase 4D antibody, lysine (K)-specific demethylase 4D antibody, KDM4D antibody, LOC524768 antibody, Kdm4d antibody, LOC617971 antibody, LOC100067461 antibody, LOC698455 antibody, LOC100514356 antibody
- 背景
- Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.
- UniProt
- Q6B0I6
- 途径
- Warburg Effect
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