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Recombinant KDM2A 抗体

This 兔 单克隆 antibody specifically detects KDM2A in WB, IHC 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7828363
发货至: 中国
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Quick Overview for Recombinant KDM2A 抗体 (ABIN7828363)

抗原

See all KDM2A 抗体
KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

抗体类型

Recombinant Antibody

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 46
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单克隆

标记

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This KDM2A antibody is un-conjugated

应用范围

  • 28
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

克隆位点

A401
  • 原理

    Recombinant KDM2A Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human KDM2A fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:1000-1:5000,IHC 1:50-1:100,IF 1:50

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

    别名

    KDM2A

    背景

    CXXC,FBXL,KIAA,FBL,KDM2A,CXXC8,FBL11,FBL7,FBXL11,JHDM1A,LILINA,lysine demethylase 2A,KIAA1004,CXXC8,FBL11,FBL7,FBXL11,JHDM1A,LILINA,lysine demethylase 2A,[Histone-H3]-lysine-36 demethylase 1A,CXXC-type zinc finger protein 8,F box / LRR repeat protein 11,F box and leucine rich repeat protein 11,F box protein FBL7,F-box and leucine-rich repeat protein 11,F-box protein FBL7,F-box protein Lilina,F-box/LRR-repeat protein 11,JmjC domain-containing histone demethylation protein 1A,Jumonji C domain containing histone demethylase 1A,Lysine (K) specific demethylase 2A,Lysine-specific demethylase 2A,Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and Trimethylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis. Regulates circadian gene expression by repressing the transcriptional activator activity of CLOCK-ARNTL/BMAL1 heterodimer and RORA in a catalytically-independent manner. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 133 kDa

    Observed MW: 140 kDa The actual band is not consistent with the expectation.

    UniProt

    Q9Y2K7

    途径

    Warburg Effect
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