Recombinant KDM2A 抗体
Our Local Distributor
北京 101111
Quick Overview for Recombinant KDM2A 抗体 (ABIN7828363)
抗原
See all KDM2A 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Recombinant KDM2A Monoclonal Antibody
-
纯化方法
- Protein A purified
-
免疫原
- Recombinant human KDM2A fragment
-
亚型
- IgG, kappa
-
-
-
-
应用备注
- WB 1:1000-1:5000,IHC 1:50-1:100,IF 1:50
-
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
-
有效期
- 12 months
-
-
- KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))
-
别名
- KDM2A
-
背景
- CXXC,FBXL,KIAA,FBL,KDM2A,CXXC8,FBL11,FBL7,FBXL11,JHDM1A,LILINA,lysine demethylase 2A,KIAA1004,CXXC8,FBL11,FBL7,FBXL11,JHDM1A,LILINA,lysine demethylase 2A,[Histone-H3]-lysine-36 demethylase 1A,CXXC-type zinc finger protein 8,F box / LRR repeat protein 11,F box and leucine rich repeat protein 11,F box protein FBL7,F-box and leucine-rich repeat protein 11,F-box protein FBL7,F-box protein Lilina,F-box/LRR-repeat protein 11,JmjC domain-containing histone demethylation protein 1A,Jumonji C domain containing histone demethylase 1A,Lysine (K) specific demethylase 2A,Lysine-specific demethylase 2A,Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and Trimethylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis. Regulates circadian gene expression by repressing the transcriptional activator activity of CLOCK-ARNTL/BMAL1 heterodimer and RORA in a catalytically-independent manner. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
-
分子量
-
Calculated MW: 133 kDa
Observed MW: 140 kDa The actual band is not consistent with the expectation.
-
UniProt
- Q9Y2K7
-
途径
- Warburg Effect
抗原
-