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Recombinant Histone H2B 抗体 (H2BK46ac)

This 兔 单克隆 antibody specifically detects Histone H2B in WB, IF 和 ChIP. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7828264
发货至: 中国
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中国
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Beijing Economic Technological Development Area
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Quick Overview for Recombinant Histone H2B 抗体 (H2BK46ac) (ABIN7828264)

抗原

See all Histone H2B 抗体
Histone H2B

抗体类型

Recombinant Antibody

适用

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人, 小鼠, 大鼠

宿主

  • 280
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克隆类型

  • 218
  • 87
单克隆

标记

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This Histone H2B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP)

克隆位点

A101
  • 抗原表位

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    H2BK46ac

    原理

    Recombinant Histone H2B (Acetyl Lys46) Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Acetylated human histone H2B (Lys46) peptide

    亚型

    IgG, kappa
  • 应用备注

    WB 1:500-1:2000,ChIP 6 μg/5x106 cells,IF 1:200

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    Histone H2B

    背景

    HIST1H2BG,H2B.1A,H2B/a,H2BFA,H2BFL,HIST1H2BC,H2BFH,HIST1H2BE,H2BFG,HIST1H2BF,H2BFK,HIST1H2BI,H2BC4,H2BC6,H2BC7,H2BC8,H2BC10,Histone post-translational modifications (PTMs) are key mechanisms of epigenetics that modulate chromatin structures, termed as ""histone code"". The PTMs on histone including acetylation, methylation, phosphorylation and novel acylations directly affect the accessibility of chromatin to transcription factors and other epigenetic regulators, altering genome stability, gene transcription, etc. Histone acetylation occurs primarily at multiple lysine residues on the amino-terminal of core histones, in response to various stimuli and plays vital roles in the regulation of gene expression, DNA damage repair, chromatin dynamics, etc. Mostly, histone H2A is primarily acetylated at Lys5, 9, 15, and 36, H2B is primarily acetylated at Lys5, 12, 15, 16, and 20. Histone H3 is primarily acetylated at Lys4, 9, 14, 18, 23, 27, 56, and 79. Histone H4 is primarily acetylated at Lys5, 8, 12, 16, and 20. Histone acetyltransferases (HATs) and histone deacetylases (HDACs) are major regulating factors. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 14 kDa

    Observed MW: 15kDa The actual band is not consistent with the expectation.

    UniProt

    P62807
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