Recombinant Histone H2A 抗体 (H2AK5ac)
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北京 101111
Quick Overview for Recombinant Histone H2A 抗体 (H2AK5ac) (ABIN7828262)
抗原
See all Histone H2A 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- H2AK5ac
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原理
- Recombinant Histone H2A (Acetyl Lys5) Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Acetylated human histone H2A (Lys5) peptide
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亚型
- IgG, kappa
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应用备注
- WB 1:1000-1:2000,ChIP 6 μg/ 5x106 cells
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- Histone H2A
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背景
- H2AFM,HIST1H2AB,H2AFA,HIST1H2AE,H2AC4,H2AC8,Histone post-translational modifications (PTMs), known as the ""histone code"", are key mechanisms of epigenetics that modulate chromatin structures. The PTMs on histone including acetylation, methylation, phosphorylation, and novel acylations directly affect the accessibility of chromatin to transcription factors and other epigenetic regulators, altering genome stability and gene transcription. Histone acetylation, tightly controlled by the opposing action of histone acetyltransferases (HATs) and histone deacetylases (HDACs), occurs primarily at lysine residues on the N-terminal tails of histones H2A (Lys5, 9, and 15), H2B (Lys5, 12, 15, 16, and 20), H3 (Lys4, 9, 14, 18, 23, 27, and 36), and H4 (Lys5, 8, 12, 16, and 20), and plays vital roles in the regulation of gene expression, DNA damage repair, chromatin dynamics, etc. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 14 kDa
Observed MW: 14 kDa
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UniProt
- P04908
抗原
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