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Recombinant HMGB1 抗体

The 兔 单克隆 anti-HMGB1 antibody is suitable to detect HMGB1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC, FACS 和 IP.
产品编号 ABIN7828259
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant HMGB1 抗体 (ABIN7828259)

抗原

See all HMGB1 抗体
HMGB1 (High Mobility Group Box 1 (HMGB1))

抗体类型

Recombinant Antibody

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 133
  • 75
单克隆

标记

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This HMGB1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP)

克隆位点

A253
  • 原理

    Recombinant HMGB1 Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human HMGB1 fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:500-1:2000,IHC 1:200-1:1000,FCM 1:50-1:100,IP 1:25

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    HMGB1 (High Mobility Group Box 1 (HMGB1))

    别名

    HMGB1

    背景

    SBP,HMGB,High Mobility Group Protein,High mobility group protein B,HMG,HMG-1,HMG1,HMG3,SBP-1,HMGB1,Amphoterin,High Mobility Group Protein 1,High mobility group protein B1,High mobility group protein 1 (HMG-1),High mobility group protein 1,high mobility group protein B1,high-mobility group box 1,HMG1,HMG-1,HMG1DKFZp686A04236,HMG3,HMGB1,SBP-1,Chromosomal protein,DKFZp686A04236,High mobility group 1,High mobility group box 1,high-mobility group (nonhistone chromosomal) protein 1,HMGB 1,nonhistone,NONHISTONE CHROMOSOMAL PROTEIN HMG1,SBP 1,Sulfoglucuronyl carbohydrate binding protein,Multifunctional redox sensitive protein with various roles in different cellular compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair and genome stability. Proposed to be an universal biosensor for nucleic acids. Promotes host inflammatory response to sterile and infectious signals and is involved in the coordination and integration of innate and adaptive immune responses. In the cytoplasm functions as sensor and/or chaperone for immunogenic nucleic acids implicating the activation of TLR9-mediated immune responses, and mediates autophagy. Acts as danger associated molecular pattern (DAMP) molecule that amplifies immune responses during tissue injury. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 25 kDa

    Observed MW: 25 kDa

    UniProt

    P09429

    途径

    p53 Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome
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