Recombinant HMGB1 抗体
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北京 101111
Quick Overview for Recombinant HMGB1 抗体 (ABIN7828259)
抗原
See all HMGB1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant HMGB1 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human HMGB1 fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:500-1:2000,IHC 1:200-1:1000,FCM 1:50-1:100,IP 1:25
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- HMGB1 (High Mobility Group Box 1 (HMGB1))
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别名
- HMGB1
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背景
- SBP,HMGB,High Mobility Group Protein,High mobility group protein B,HMG,HMG-1,HMG1,HMG3,SBP-1,HMGB1,Amphoterin,High Mobility Group Protein 1,High mobility group protein B1,High mobility group protein 1 (HMG-1),High mobility group protein 1,high mobility group protein B1,high-mobility group box 1,HMG1,HMG-1,HMG1DKFZp686A04236,HMG3,HMGB1,SBP-1,Chromosomal protein,DKFZp686A04236,High mobility group 1,High mobility group box 1,high-mobility group (nonhistone chromosomal) protein 1,HMGB 1,nonhistone,NONHISTONE CHROMOSOMAL PROTEIN HMG1,SBP 1,Sulfoglucuronyl carbohydrate binding protein,Multifunctional redox sensitive protein with various roles in different cellular compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair and genome stability. Proposed to be an universal biosensor for nucleic acids. Promotes host inflammatory response to sterile and infectious signals and is involved in the coordination and integration of innate and adaptive immune responses. In the cytoplasm functions as sensor and/or chaperone for immunogenic nucleic acids implicating the activation of TLR9-mediated immune responses, and mediates autophagy. Acts as danger associated molecular pattern (DAMP) molecule that amplifies immune responses during tissue injury. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 25 kDa
Observed MW: 25 kDa
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UniProt
- P09429
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途径
- p53 Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome
抗原
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