Recombinant HSPE1 抗体
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北京 101111
Quick Overview for Recombinant HSPE1 抗体 (ABIN7828249)
抗原
See all HSPE1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant Cpn10 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human Cpn10 fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:500-1:1000,IHC 1:200-1:1000,IF 1:50
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- HSPE1 (Heat Shock 10kDa Protein 1 (Chaperonin 10) (HSPE1))
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别名
- Cpn10
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背景
- CPN,HSP,HSPE,HSPE1,CPN10,EPF,GROES,HSP10,10 kDa chaperonin,10 kDa heat shock protein,10 kDa heat shock protein mitochondrial,CH10,Chaperonin 10,Chaperonin 10 homolog,cpn10 homolog,Early pregnancy factor,Early-pregnancy factor,GroES homolog,Heat shock 10kD protein 1 chaperonin 10,Heat shock 10 kDa protein 1,Heat shock 10 kDa protein 1 chaperonin 10,Heat shock protein family E (Hsp10) member,Heat-shock 10-kD protein,mitochondrial,Co-chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp60, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10. This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components. Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 11 kDa
Observed MW: 11 kDa
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UniProt
- P61604
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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