Recombinant FOXC1 抗体
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北京 101111
Quick Overview for Recombinant FOXC1 抗体 (ABIN7828213)
抗原
See all FOXC1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant FOXC1 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human FOXC1 fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:1000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- FOXC1 (Forkhead Box C1 (FOXC1))
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别名
- FOXC1
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背景
- IHG,FOXC,ASGD,FKHL,IRID,RIEG,FOXC1,ARA,ASGD3,FKHL7,FREAC-3,FREAC3,IGDA,IHG1,IRID1,RIEG3,FKH L7,FKHL 7,Forkhead (Drosophila) like 7,Forkhead box C1,Forkhead box protein C1,Forkhead drosophila homolog like 7,Forkhead like 7,Forkhead related activator 3,Forkhead related protein FKHL7,Forkhead related transcription factor 3,Forkhead-related protein FKHL7,Forkhead-related transcription factor 3,FOX C1,FOXC 1,FREAC 3,IHG 1,IRID 1,Iridogoniodysgenesis type 1,Myeloid factor delta,FoxC1, also named as FKHL7 or FREAC3, is one of two mammalian FoxC subfamily members. Along with FoxC2, it is expressed in paraxial mesoderm where it functions to promote somitogenesis, myogenesis, and vascular development, possibly under Wnt/β-catenin regulation. Mutations in FoxC1 are implicated in anterior segment dysgenesis (ASD) disorders, including congenital glaucoma and Axenfeld-Rieger syndrome. Research studies have shown that alterations in FoxC1 expression are linked to breast cancer invasiveness and have been shown to modulate proliferation and migration of breast cancer cells in vitro. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 70-74 kDa
Observed MW: 70 kDa The actual band is not consistent with the expectation.
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UniProt
- Q12948
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途径
- Chromatin Binding, Glycosaminoglycan Metabolic Process
抗原
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