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Recombinant FOXC1 抗体

This 兔 单克隆 antibody specifically detects FOXC1 in WB. It exhibits reactivity toward 人.
产品编号 ABIN7828213
发货至: 中国
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Quick Overview for Recombinant FOXC1 抗体 (ABIN7828213)

抗原

See all FOXC1 抗体
FOXC1 (Forkhead Box C1 (FOXC1))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

  • 55
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单克隆

标记

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This FOXC1 antibody is un-conjugated

应用范围

  • 45
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Western Blotting (WB)

克隆位点

A663
  • 原理

    Recombinant FOXC1 Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human FOXC1 fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:1000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    FOXC1 (Forkhead Box C1 (FOXC1))

    别名

    FOXC1

    背景

    IHG,FOXC,ASGD,FKHL,IRID,RIEG,FOXC1,ARA,ASGD3,FKHL7,FREAC-3,FREAC3,IGDA,IHG1,IRID1,RIEG3,FKH L7,FKHL 7,Forkhead (Drosophila) like 7,Forkhead box C1,Forkhead box protein C1,Forkhead drosophila homolog like 7,Forkhead like 7,Forkhead related activator 3,Forkhead related protein FKHL7,Forkhead related transcription factor 3,Forkhead-related protein FKHL7,Forkhead-related transcription factor 3,FOX C1,FOXC 1,FREAC 3,IHG 1,IRID 1,Iridogoniodysgenesis type 1,Myeloid factor delta,FoxC1, also named as FKHL7 or FREAC3, is one of two mammalian FoxC subfamily members. Along with FoxC2, it is expressed in paraxial mesoderm where it functions to promote somitogenesis, myogenesis, and vascular development, possibly under Wnt/β-catenin regulation. Mutations in FoxC1 are implicated in anterior segment dysgenesis (ASD) disorders, including congenital glaucoma and Axenfeld-Rieger syndrome. Research studies have shown that alterations in FoxC1 expression are linked to breast cancer invasiveness and have been shown to modulate proliferation and migration of breast cancer cells in vitro. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 70-74 kDa

    Observed MW: 70 kDa The actual band is not consistent with the expectation.

    UniProt

    Q12948

    途径

    Chromatin Binding, Glycosaminoglycan Metabolic Process
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