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Recombinant DDB2 抗体

The 兔 单克隆 anti-DDB2 antibody is suitable to detect DDB2 in samples from 人. It has been validated for WB 和 IHC.
产品编号 ABIN7828148
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant DDB2 抗体 (ABIN7828148)

抗原

See all DDB2 抗体
DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This DDB2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

A636
  • 原理

    Recombinant DDB2 Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human DDB2 fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:1000,IHC 1:500-1:1000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))

    别名

    DDB2

    背景

    DDB,UV-DDB,DDB2,DDBB,UV-DDB2,XPE,DamagedDNA-Binding Protein (DDB) consists of a 127 kDa subunit (DDB-1) and a 48 kDa subunit (DDB-2) that contribute to the formation of the UV-damaged DNA-binding protein complex (UV-DDB). In conjunction with CUL4A and ROC-1, the UV-DDB complex forms an E3 ubiquitin ligase that recognizes a broad spectrum of DNA lesions such as cyclobutane pyrimidine dimers, 6-4 photoproducts, apurinic sites and short mismatches. The complex polyubiquitinates components of the nucleotide excision repair pathway. Loss of DDB activity has been identified in a subset of xeroderma pigmentosum complementation group E (XP-E) patients and has been linked to the deficient repair of cyclobutane pyrimidine dimers in cells derived from these patients. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 48 kDa

    Observed MW: 48 kDa

    UniProt

    Q92466

    途径

    DNA Damage Repair
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