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Recombinant Clusterin 抗体

This 兔 单克隆 antibody specifically detects Clusterin in WB. It exhibits reactivity toward 大鼠 和 小鼠.
产品编号 ABIN7828120
发货至: 中国
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Quick Overview for Recombinant Clusterin 抗体 (ABIN7828120)

抗原

See all Clusterin (CLU) 抗体
Clusterin (CLU)

抗体类型

Recombinant Antibody

适用

  • 105
  • 50
  • 49
  • 21
  • 10
  • 7
  • 2
  • 2
  • 2
  • 1
大鼠, 小鼠

宿主

  • 125
  • 42
  • 10
  • 5
  • 4
  • 2
  • 1

克隆类型

  • 106
  • 78
  • 2
单克隆

标记

  • 101
  • 29
  • 16
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
This Clusterin antibody is un-conjugated

应用范围

  • 155
  • 101
  • 54
  • 43
  • 36
  • 24
  • 22
  • 15
  • 8
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

克隆位点

A616
  • 原理

    Recombinant Clusterin beta Chain Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human Clusterin beta Chain fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:500-1:1000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    Clusterin (CLU)

    别名

    Clusterin beta Chain

    背景

    KUB,AAG,Ku70-binding protein,Sulfated glycoprotein,Complement-associated protein SP,Testosterone-repressed prostate message,NA1/NA,SGP,CLU,AAG4,APO-J,APOJ,CLI,CLU1,CLU2,KUB1,NA1/NA2,SGP-2,SGP2,SP-40,TRPM-2,TRPM2,clusterin,CLUS,Aging-associated gene 4 protein,Apolipoprotein J,Complement cytolysis inhibitor,Complement-associated protein SP-40,Ku70-binding protein 1,Sulfated glycoprotein2,Testosterone-repressed prostate message 2,Complement cytolysis inhibitor a chain,Clusterin alpha chain,Complement cytolysis inhibitor b chain,APOJ CLI,Sulfated glycoprotein 2,Clusterin (CLU) also named as apolipoprotein J, is a multifunctional glycoprotein that is expressed ubiquitously in most tissues. Clusterin functions as a secreted chaperone protein that interacts with and stabilizes stress-induced proteins to prevent their precipitation. Research studies show that clusterin plays a protective role in Alzheimer's disease by sequestering amyloid β (1-40) peptides to form long-lived, stable complexes, which prevents amyloid fibril formation.In addition to the secreted protein, several intracellular isoforms are localized to the nucleus, mitochondria, cytoplasm and ER. The subcellular distribution of these multiple isoforms leads to the diversity of clusterin functions. Additional studies report that clusterin is involved in membrane recycling, cell adhesion, cell proliferation, apoptosis, and tumor survival. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 52 kDa

    Observed MW: 35 kDa The actual band is not consistent with the expectation.

    UniProt

    P10909

    途径

    Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
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