Recombinant CHD1 抗体
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北京 101111
Quick Overview for Recombinant CHD1 抗体 (ABIN7828112)
抗原
See all CHD1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant CHD1 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human CHD1 fragment
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亚型
- IgG, kappa
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anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (C-Term) antibody
CHD1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (AA 1501-1710) antibodyCHD1 适用: 人 ELISA, IHC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (AA 1177-1272) antibodyCHD1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (AA 1177-1272) antibodyCHD1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (C-Term) antibodyCHD1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (AA 1177-1272) antibodyCHD1 适用: 人 WB, ELISA, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) antibodyCHD1 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (AA 1331-1380) antibodyCHD1 适用: 人, 小鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (AA 251-467) antibodyCHD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))
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别名
- CHD1
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背景
- CHD,chromodomain-helicase-DNA-binding protein,CHD1,chromodomain-helicase-DNA-binding protein 1,CHD1 belongs to the SNF2/RAD54 helicase family. CHD1 is an aTP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. CHD1 regulates polymerase II transcription. It is required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step. CHD1 negatively regulates DNA replication. CHD1 is associated with histone deacetylase (HDAC) activity. CHD1 is required for the bridging of SNF2, the FACT complex, the PAF complex as well as the U2 snRNP complex to H3K4me3. It functions to modulate the efficiency of pre-mRNA splicing in part through physical bridging of spliceosomal components to H3K4me3. It is required for maintaining open chromatin and pluripotency in embryonic stem cells. In PTEN-deficient prostate and breast cancers, CHD1 depletion profoundly and specifically suppressed cell proliferation, cell survival and tumorigenic potential. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 197 kDa
Observed MW: 250 kDa The actual band is not consistent with the expectation.
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UniProt
- O14646
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途径
- Chromatin Binding
抗原
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