CHD1 抗体 (AA 251-467)
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北京 101111
Quick Overview for CHD1 抗体 (AA 251-467) (ABIN2668525)
抗原
See all CHD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 251-467
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原理
- CHD1 antibody (pAb)
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纯化方法
- Unpurified
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免疫原
- This CHD1 antibody was raised against a recombinant protein corresponding to amino acids 251-467 of human CHD1.
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anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (C-Term) antibody
CHD1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (AA 1177-1272) antibodyCHD1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (AA 1501-1710) antibodyCHD1 适用: 人 ELISA, IHC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (AA 1177-1272) antibodyCHD1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (AA 1660-1710) antibodyCHD1 适用: 人 WB, IP, ChIP, ChIP-seq 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (AA 71-1250) antibodyCHD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (C-Term) antibodyCHD1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (AA 1177-1272) antibodyCHD1 适用: 人 WB, ELISA, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (AA 1331-1380) antibodyCHD1 适用: 人, 小鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500 - 1:1,000 dilution The addition of 0.05 % Tween 20 in the blocking buffer and primary antibody incubation buffer is recommended to aid in detection by Western blot. Individual optimization may be required.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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: "The nucleosomal barrier to promoter escape by RNA polymerase II is overcome by the chromatin remodeler Chd1." in: eLife, Vol. 3, pp. e02042, (2014) (PubMed).
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- CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))
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别名
- CHD1
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背景
- CHD (Chromo-ATPase/Helicase-DNA-binding) proteins, which are ATP-dependent chromatin remodeling factors implicated in RNA polymerase II transcriptional regulation, are characterized by the presence of a double chromodomains (Chromatin Organization Modifier) and SNF2-related helicase/ATPase domains. The CHD1/CHD2 sub-family of CHD proteins also contain a C-terminal DNA binding domain that recognizes AT-rich sequences. CHD proteins alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. CHD1 has been shown to interact with histone H3 trimethylated at lysine 4 (H3K4Me3) and also is required for the maintenance of stem cell pluripotency.
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分子量
- 220 kDa
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基因ID
- 1105
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NCBI登录号
- NP_001261
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途径
- Chromatin Binding
抗原
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