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CHD1 抗体 (C-Term)

CHD1 适用: 人, 小鼠 WB, IF, ICC 宿主: 大鼠 Monoclonal 2F11 unconjugated
产品编号 ABIN6971529
发货至: 中国
  • 抗原 See all CHD1 抗体
    CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))
    抗原表位
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 31
    • 15
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 23
    • 5
    • 3
    • 1
    大鼠
    克隆类型
    • 28
    • 4
    单克隆
    标记
    • 24
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHD1 antibody is un-conjugated
    应用范围
    • 21
    • 12
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    产品特性
    CHD1 (Chromo-ATPase/Helicase-DNA-binding protein 1 ) is a member of the CHD family of ATP-dependent chromatin remodeling factors implicated in RNA polymerase II transcriptional regulation. They are characterized by the presence of a double chromodomains (Chromatin Organization Modifier) and SNF2-related helicase/ATPase domains. The CHD1/CHD2 sub-family of CHD proteins also contain a C-terminal DNA binding domain that recognizes AT-rich sequences. CHD proteins alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. CHD1 has been shown to interact with histone H3 trimethylated at lysine 4 (H3K4Me3) and also is required for the maintenance of stem cell pluripotency. CHD1 antibody (mAb) (Clone 2F11) was raised in a Rat host. It has been validated for use in Immunocytochemistry, Immunofluorescence and Western blot, it has been shown to react with Human and Mouse samples.
    纯化方法
    Protein G Chromatography
    免疫原
    This CHD1 antibody was raised against a peptide corresponding to the C-terminus of mouse CHD1.
    克隆位点
    2F11
    亚型
    IgG2a
    Top Product
    Discover our top product CHD1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • 抗原
    CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))
    别名
    CHD1 (CHD1 产品)
    别名
    CHD-1 antibody, 4930525N21Rik antibody, AI851787 antibody, AW555109 antibody, CHD1 antibody, CG3733 antibody, DmCHD1 antibody, Dmel\\CG3733 antibody, chd1 antibody, dCHD1 antibody, l(2)23Cd antibody, CHD1W antibody, chromodomain helicase DNA binding protein 1 antibody, Chromodomain-helicase-DNA-binding protein antibody, Chromodomain-helicase-DNA-binding protein 1 antibody, CHD1 antibody, Chd1 antibody, CHDB1 antibody
    分子量
    210 kDa
    NCBI登录号
    NP_031716
    途径
    Chromatin Binding
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