Recombinant CD3D 抗体
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北京 101111
Quick Overview for Recombinant CD3D 抗体 (ABIN7828082)
抗原
See all CD3D 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant CD3D Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human CD3D fragment
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亚型
- IgG, kappa
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anti-CD3d Molecule, delta (CD3-TCR Complex) (CD3D) (AA 127-171) antibody
CD3D 适用: 人 ICC, ELISA, FACS 宿主: 小鼠 Monoclonal 6B6B12 unconjugated
anti-CD3d Molecule, delta (CD3-TCR Complex) (CD3D) (AA 127-171) antibodyCD3D 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 4B9G9 unconjugated
anti-CD3d Molecule, delta (CD3-TCR Complex) (CD3D) (AA 22-105) antibodyCD3D 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1F6A8 unconjugated
anti-CD3d Molecule, delta (CD3-TCR Complex) (CD3D) (AA 18-113) antibodyCD3D 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD3d Molecule, delta (CD3-TCR Complex) (CD3D) (AA 22-105) antibodyCD3D 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD3d Molecule, delta (CD3-TCR Complex) (CD3D) (AA 1-171) antibodyCD3D 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-CD3d Molecule, delta (CD3-TCR Complex) (CD3D) (AA 127-171) antibodyCD3D 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1H12G5 unconjugated
anti-CD3d Molecule, delta (CD3-TCR Complex) (CD3D) (Internal Region) antibodyCD3D 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CD3d Molecule, delta (CD3-TCR Complex) (CD3D) antibodyCD3D 适用: 人, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD3d Molecule, delta (CD3-TCR Complex) (CD3D) (AA 22-106) antibodyCD3D 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:2000-1:10000,IHC 1:200-1:1000,IF 1:50-1:200,FCM 1:50-1:100,IP 1:25-1:50
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))
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别名
- CD3D
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背景
- IMD,CD3D,CD3-DELTA,IMD19,T3D,T-Cell Receptor T3 Delta Chain,T-cell surface glycoprotein CD3 delta chain,T3,CD3 delta,CD3D is a component of the TCR-CD3 complex, which is present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways. In addition, CD3D plays an essential role in thymocyte differentiation. It participates in correct intracellular TCR-CD3 complex assembly and surface expression. In absence of a functional TCR-CD3 complex, thymocytes are unable to differentiate properly. It interacts with CD4 and CD8 and thus serves to establish a functional link between the TCR and coreceptors CD4 and CD8, which is needed for activation and positive selection of CD4 or CD8 T-cells. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 19 kDa
Observed MW: 23 kDa The actual band is not consistent with the expectation.
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UniProt
- P04234
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途径
- TCR Signaling, CXCR4-mediated Signaling Events
抗原
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