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Recombinant CD33 抗体

This 兔 单克隆 antibody specifically detects CD33 in IHC. It exhibits reactivity toward 人.
产品编号 ABIN7828081
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant CD33 抗体 (ABIN7828081)

抗原

See all CD33 抗体
CD33

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This CD33 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

A170
  • 原理

    Recombinant CD33 Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human CD33 fragment

    亚型

    IgG, kappa
  • 应用备注

    IHC 1:200-1:1000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    CD33

    别名

    CD33

    背景

    CD33,SIGLEC-3,SIGLEC3,p67,CD33 Molecule,gp67,Myeloid cell surface antigen CD33,Sialic acid-binding Ig-like lectin 3,Siglec-3,CD33 Molecule,p67,SIGLEC3,Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state. Upon engagement of ligands such as C1q or syalylated glycoproteins, two immunoreceptor tyrosine-based inhibitory motifs (ITIMs) located in CD33 cytoplasmic tail are phosphorylated by Src-like kinases such as LCK. These phosphorylations provide docking sites for the recruitment and activation of protein-tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2. In turn, these phosphatases regulate downstream pathways through dephosphorylation of signaling molecules. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    UniProt

    P20138
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