Recombinant CD276 抗体
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北京 101111
Quick Overview for Recombinant CD276 抗体 (ABIN7828078)
抗原
See all CD276 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant B7-H3/CD276 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human B7-H3/CD276 fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:500-1:2000,IHC 1:200-1:1000,IF 1:50,FCM 1:50-1:100,IP 1:25-1:100
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- CD276
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别名
- B7-H3/CD276
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背景
- B7H,UNQ,PRO,B7-H,B7RP,B7 homolog,B7H34Ig-B7-H,PSEC,4Ig-B7-H,CD276,4Ig-B7-H3,B7-H3,B7H3,B7RP-2,B7 homolog 3,B7H34Ig-B7-H3,CD276 antigen,CD276 Molecule,Costimulatory molecule,PSEC0249,UNQ309,PRO352,B7RP-2,4Ig-B7-H3,B7H3,B7-H3,CD276 antigen,May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 57 kDa
Observed MW: 110 kDa The actual band is not consistent with the expectation.
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UniProt
- Q5ZPR3
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途径
- Cancer Immune Checkpoints
抗原
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