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Recombinant Aurora Kinase B 抗体

The 兔 单克隆 anti-Aurora Kinase B antibody (Clone A136) (ABIN7828032) specifically detects Aurora Kinase B in IHC, WB 和 IF. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7828032
发货至: 中国
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Quick Overview for Recombinant Aurora Kinase B 抗体 (ABIN7828032)

抗原

See all Aurora Kinase B (AURKB) 抗体
Aurora Kinase B (AURKB)

抗体类型

Recombinant Antibody

适用

  • 161
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人, 小鼠

宿主

  • 136
  • 45
  • 3
  • 1

克隆类型

  • 104
  • 82
单克隆

标记

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This Aurora Kinase B antibody is un-conjugated

应用范围

  • 99
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  • 14
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Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

克隆位点

A136
  • 原理

    Recombinant Aurora B Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human Aurora B fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:500-1:1000,IHC 1:50-1:100,IF 1:50

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    Aurora Kinase B (AURKB)

    别名

    Aurora B

    背景

    IPL,ARK,AIK,AIRK,PPP1R,STK,AIM,AIK2,AIM-1,AIM1,ARK2,AurB,IPL1,PPP1R48,STK12,STK5,aurkb-sv1,aurkb-sv2,AURKB,Aurora B,AIRK2,STK1,Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage: phosphorylates CHMP4C, leading to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 39 kDa

    Observed MW: 39 kDa

    UniProt

    Q96GD4

    途径

    TCR Signaling, Cell Division Cycle, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades
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