Recombinant Aurora Kinase B 抗体
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北京 101111
Quick Overview for Recombinant Aurora Kinase B 抗体 (ABIN7828032)
抗原
See all Aurora Kinase B (AURKB) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant Aurora B Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human Aurora B fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:500-1:1000,IHC 1:50-1:100,IF 1:50
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- Aurora Kinase B (AURKB)
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别名
- Aurora B
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背景
- IPL,ARK,AIK,AIRK,PPP1R,STK,AIM,AIK2,AIM-1,AIM1,ARK2,AurB,IPL1,PPP1R48,STK12,STK5,aurkb-sv1,aurkb-sv2,AURKB,Aurora B,AIRK2,STK1,Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage: phosphorylates CHMP4C, leading to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 39 kDa
Observed MW: 39 kDa
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UniProt
- Q96GD4
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途径
- TCR Signaling, Cell Division Cycle, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades
抗原
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