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Recombinant ACE2 抗体

This 兔 单克隆 antibody specifically detects ACE2 in WB 和 IHC. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN7828021
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant ACE2 抗体 (ABIN7828021)

抗原

See all ACE2 抗体
ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

抗体类型

Recombinant Antibody

适用

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人, 小鼠

宿主

  • 142
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克隆类型

  • 119
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单克隆

标记

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This ACE2 antibody is un-conjugated

应用范围

  • 139
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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

A708
  • 原理

    Recombinant ACE2 Monoclonal Antibody

    纯化方法

    Protein A purified

    亚型

    IgG, kappa
  • 应用备注

    WB 1:1000,IHC 1:500-1:1000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

    别名

    ACE2

    背景

    ACE,UNQ,PRO,Metalloprotease MPROT,Angiotensin-converting enzyme,ACE2,ACEH,ACEII,Angiotensin-converting enzyme 2,Angiotensin-converting enzyme homolog,Angiotensin-converting enzyme-related carboxypeptidase,ACE-related carboxypeptidase,Metalloprotease MPROT15,Processed angioten,UNQ868,PRO1885,ACEH,angiotensin-converting enzyme 2,ACE 2,ACE related carboxypeptidase,Angiotensin converting enzyme 2,Angiotensin converting enzyme homolog,Angiotensin converting enzyme like protein,Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2,Angiotensin I converting enzyme 2,DKFZP434A014,EC 3.4.17,metalloprotease MPROT 15,OTTHUMP00000022963,Processed angiotensin-converting enzyme 2,ACE2 is a carboxypeptidase that catalyses the conversion of angiotensin I to angiotensin 1-9, or of angiotensin II to the vasodilator angiotensin 1-7. ACE2 is a critical component in the renin-angiotensin system (RAS). ACE2 is predominantly expressed in vascular endothelial cells of the heart and kidney and Leydig and Sertoli cells of the testis. The unique expression pattern of ACE2 determines its essential role in the regulation of cardiovascular and kidney functions, as well as fertility. ACE2 protein is localized mainly in the extracellular space with its carboxy-terminal end attached to the membrane via its transmembrane domain. Active ACE2 enzyme is secreted by cleavage at the amino terminus. Research studies have shown that ACE2 expression is elevated in human failing heart. ACE2 has also been identified as the receptor for SARS and SARS-CoV-2 coronaviruses. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 92 kDa

    Observed MW: 100, 120 kDa The actual band is not consistent with the expectation.

    UniProt

    Q9BYF1

    途径

    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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