Recombinant HMGCR 抗体
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北京 101111
Quick Overview for Recombinant HMGCR 抗体 (ABIN7827985)
抗原
See all HMGCR 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant HMGCR Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human HMG-CoA Reductase fragment
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亚型
- IgG, kappa
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anti-3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 629-888) antibody
HMGCR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 638-887) antibodyHMGCR 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (pSer872) antibodyHMGCR 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 588-887) antibodyHMGCR 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (N-Term) antibodyHMGCR 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 251-350) antibodyHMGCR 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) antibodyHMGCR 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4895 unconjugated Recombinant Antibody
anti-3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) antibodyHMGCR 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB6220 unconjugated Recombinant Antibody
anti-3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (Internal Region) antibodyVerified HMGCR 适用: 人 ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 1-835) antibodyHMGCR 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000,IF 1:50,FCM 1:50-1:100,IP 1:25
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))
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别名
- HMGCR
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背景
- LDLCQ,HMGCR,LDLCQ3,3-hydroxy-3-methylglutaryl-CoA reductase,3-hydroxy-3-methylglutaryl-CoA reductase,LDLCQ3,3-hydroxy-3-methylglutaryl-coenzyme A reductase,HMG-CoA reductase,3-Hydroxy-3-methylglutaryl-CoA reductase (HMGCR) is a transmembrane glycoprotein of the endoplasmic reticulum. It is the rate-limiting enzyme for cholesterol biosynthesis and non-sterol isoprenoid biosynthesis. Play a key role in cellular cholesterol homeostasis. The activity of HMGCR is regulated by negative feedback, in which cholesterol and other end products of the metabolic pathway inhibit the activity of HMGCR in a multivalent manner. Cholesterol inhibits reductase activity mainly by inhibiting the transcription rate of HMGCR gene. HMGCR is the main target of statins, which are a class of cholesterol-lowering drugs. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 97 kDa
Observed MW: 97 kDa
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UniProt
- P04035
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途径
- AMPK Signaling, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha
抗原
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