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SOD2 抗体 (AA 1-224)

This 兔 多克隆 anti-SOD2 antibody specifically detects SOD2 in WB. The antibody is reactive with 斑马鱼 samples.
产品编号 ABIN7825888
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SOD2 抗体 (AA 1-224) (ABIN7825888)

抗原

See all SOD2 抗体
SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))

适用

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斑马鱼

宿主

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克隆类型

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多克隆

标记

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This SOD2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    AA 1-224

    原理

    Anti-Zebrafish SOD2 Antibody

    产品特性

    Anti-Zebrafish SOD2 Antibody catalog #AZQ6P980. Tested in WB applications. This antibody reacts with Zebrafish. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived zebrafish SOD2 recombinant protein (Position: M1-K224)

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Zebrafish

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))

    别名

    SOD2

    背景

    SOD2(Superoxide Dismutase 2), also called IPO-B or MNSOD, is a mitochondrial matrix enzyme that scavenges oxygen radicals produced by the extensive oxidation-reduction and electron transport reactions occurring in mitochondria. This gene is a member of the iron/manganese superoxide dismutase family. Using a somatic cell hybrid panel containing different segments of chromosome 6, they demonstrated that SOD2 is located in the region 6q25.3-qter which, together with the FISH analysis, indicated that SOD2 is in the distal portion of 6q25. The SOD2 gene encodes an intramitochondrial free radical scavenging enzyme that is the first line of defense against superoxide produced as a byproduct of oxidative phosphorylation. Adeno-associated viral delivery of the human SOD2 gene resulted in suppression of optic nerve degeneration and rescue of retinal ganglion cells. The findings suggested that reactive oxygen species contributed to retinal cell death and optic nerve damage in mice with complex I deficiency, and that expression of SOD2 attenuated the disease process.

    分子量

    25 kDa

    UniProt

    Q6P980

    途径

    Sensory Perception of Sound, Transition Metal Ion Homeostasis, Negative Regulation of intrinsic apoptotic Signaling
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