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ASH2L 抗体 (AA 95-584)

This anti-ASH2L antibody is a 兔 多克隆 antibody detecting ASH2L in IHC 和 IF. Suitable for 斑马鱼.
产品编号 ABIN7825813
发货至: 中国

Quick Overview for ASH2L 抗体 (AA 95-584) (ABIN7825813)

抗原

See all ASH2L 抗体
ASH2L (Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))

适用

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斑马鱼

宿主

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克隆类型

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多克隆

标记

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This ASH2L antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 95-584

    原理

    Anti-Zebrafish ASH2L Antibody

    产品特性

    Anti-Zebrafish ASH2L Antibody catalog # AZA0A8M2B2E1. Tested in IHC, IF applications. This antibody reacts with Zebrafish.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived zebrafish ASH2L recombinant protein (Position: N95-G584).

    亚型

    IgG
  • 应用备注

    Immunohistochemistry, 2-5 μg/mL, Zebrafish
    Immunofluorescence, 5 μg/mL, Zebrafish

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    ASH2L (Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))

    别名

    ASH2L

    背景

    Set1/Ash2 histone methyltransferase complex subunit ASH2 is an enzyme that in humans is encoded by the ASH2L gene. The Set1 histone methyltransferase protein was first identified in yeast as part of the Set1/COMPASS histone methyltransferase complex, which methylates histone H3 at Lys4 and functions as a transcriptional co-activator. While yeast contain only one known Set1 protein, six Set1-related proteins exist in mammals: SET1A, SET1B, MLL1, MLL2, MLL3, and MLL4, all of which assemble into COMPASS-like complexes and methylate histone H3 at Lys4. These Set1-related proteins are each found in distinct protein complexes, all of which share the common subunits WDR5, RBBP5, ASH2L, CXXC1 and DPY30. These subunits are required for proper complex assembly and modulation of histone methyltransferase activity. MLL1 and MLL2 complexes contain the additional protein subunit, menin. Like yeast Set1, all six Set1-related mammalian proteins methylate histone H3 at Lys4. MLL translocations are found in a large number of hematological malignancies, suggesting that Set1/COMPASS histone methyltransferase complexes play a critical role in leukemogenesis.

    UniProt

    A0A8M2B2E1
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