OAZ1 抗体 (N-Term)
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北京 101111
Quick Overview for OAZ1 抗体 (N-Term) (ABIN7825645)
抗原
See all OAZ1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-OAZ1 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-OAZ1 Antibody catalog # A06486-4. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human OAZ1. Human OAZ1 shares 100% amino acid (aa) sequence identity with both mouse and rat OAZ1.
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亚型
- IgG
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anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (AA 1-68) antibody
OAZ1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (AA 1-68) antibodyOAZ1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (N-Term) antibodyOAZ1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (AA 120-132) antibodyVerified OAZ1 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (AA 2-31), (N-Term) antibodyOAZ1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB18521 unconjugated
anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (N-Term) antibodyOAZ1 适用: 人, 小鼠, 大鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (AA 14-63) antibodyOAZ1 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry, 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- OAZ1 (Ornithine Decarboxylase Antizyme 1 (OAZ1))
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别名
- OAZ1
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背景
- The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis, thus, completing the auto-regulatory circuit. This gene encodes antizyme 1, the first member of the antizyme family, that has broad tissue distribution, and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradation, as well as inhibiting polyamine uptake. Antizyme 1 mRNA contains two potential in-frame AUGs, and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization. Alternatively spliced transcript variants have also been noted for this gene.
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分子量
- 25 kDa
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基因ID
- 4946
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UniProt
- P54368
抗原
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