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OAZ1 抗体 (N-Term)

This anti-OAZ1 antibody is a 兔 多克隆 antibody detecting OAZ1 in IHC, WB 和 FACS. Suitable for 人.
产品编号 ABIN7825645
发货至: 中国

Quick Overview for OAZ1 抗体 (N-Term) (ABIN7825645)

抗原

See all OAZ1 抗体
OAZ1 (Ornithine Decarboxylase Antizyme 1 (OAZ1))

适用

  • 20
  • 14
  • 6

宿主

  • 19
  • 1

克隆类型

  • 20
多克隆

标记

  • 13
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This OAZ1 antibody is un-conjugated

应用范围

  • 9
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  • 1
Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS)
  • 抗原表位

    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    Anti-OAZ1 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-OAZ1 Antibody catalog # A06486-4. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human OAZ1. Human OAZ1 shares 100% amino acid (aa) sequence identity with both mouse and rat OAZ1.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry, 2-5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    OAZ1 (Ornithine Decarboxylase Antizyme 1 (OAZ1))

    别名

    OAZ1

    背景

    The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis, thus, completing the auto-regulatory circuit. This gene encodes antizyme 1, the first member of the antizyme family, that has broad tissue distribution, and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradation, as well as inhibiting polyamine uptake. Antizyme 1 mRNA contains two potential in-frame AUGs, and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization. Alternatively spliced transcript variants have also been noted for this gene.

    分子量

    25 kDa

    基因ID

    4946

    UniProt

    P54368
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