OAZ1 抗体 (AA 14-63)
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Quick Overview for OAZ1 抗体 (AA 14-63) (ABIN1535135)
抗原
See all OAZ1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 14-63
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原理
- AZ1 Antibody
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特异性
- AZ1 Polyclonal Antibody detects endogenous levels of AZ1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human OAZ1. AA range:14-63
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亚型
- IgG
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anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (AA 1-68) antibody
OAZ1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (AA 2-31), (N-Term) antibodyOAZ1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB18521 unconjugated
anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (AA 120-132) antibodyVerified OAZ1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (AA 1-68) antibodyOAZ1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (N-Term) antibodyOAZ1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (N-Term) antibodyOAZ1 适用: 人, 小鼠, 大鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:40000,WB 1:500-2000. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- OAZ1 (Ornithine Decarboxylase Antizyme 1 (OAZ1))
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别名
- OAZ1
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背景
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Synonyms: OAZ1, OAZ, Ornithine decarboxylase antizyme 1, ODC-Az
Background: The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis, thus, completing the auto-regulatory circuit.This gene encodes antizyme 1, the first member of the antizyme family, that has broad tissue distribution, and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradation, as well as inhibiting polyamine uptake. Antizyme 1 mRNA contains two potential in-frame AUGs, and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms
Gene Name: OAZ1
Protein Name: Ornithine decarboxylase antizyme 1
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分子量
- 25 kDa
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基因ID
- 4946
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OMIM
- 601579
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UniProt
- P54368
抗原
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