ACO2 抗体 (AA 651-750)
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北京 101111
Quick Overview for ACO2 抗体 (AA 651-750) (ABIN739590)
抗原
See all ACO2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 651-750
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预测反应
- Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Aconitase 2
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亚型
- IgG
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anti-Aconitase 2, Mitochondrial (ACO2) (AA 541-555) antibody
Verified ACO2 适用: 人, 大鼠, 小鼠, Pig WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Aconitase 2, Mitochondrial (ACO2) antibodyKD Validated ACO2 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB1585 unconjugated Recombinant Antibody
anti-Aconitase 2, Mitochondrial (ACO2) (AA 438-467) antibodyACO2 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB9338 unconjugated
anti-Aconitase 2, Mitochondrial (ACO2) (AA 452-676) antibodyACO2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aconitase 2, Mitochondrial (ACO2) antibodyACO2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aconitase 2, Mitochondrial (ACO2) (AA 294-325) antibodyACO2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB14646 unconjugated
anti-Aconitase 2, Mitochondrial (ACO2) antibodyACO2 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 8H4 unconjugated Recombinant Antibody
anti-Aconitase 2, Mitochondrial (ACO2) (Internal Region) antibodyVerified ACO2 适用: 人 WB, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Aconitase 2, Mitochondrial (ACO2) (N-Term) antibodyACO2 适用: 人, 大鼠, 小鼠, Cow, 犬, Saccharomyces cerevisiae, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Aconitase 2, Mitochondrial (ACO2) (Center) antibodyACO2 适用: 人, 大鼠, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- ACO2 (Aconitase 2, Mitochondrial (ACO2))
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别名
- Aconitase 2
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背景
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Synonyms: ACO 2, ACO2, aconitase 2, Aconitase 2 mitochondrial, Aconitase, Aconitase2, Aconitate hydratase, Aconitate hydratase mitochondrial, ACONM, Citrate hydro lyase.
Background: ACO2, also referred to as aconitate hydratase, citrate hydrolyase or aconitase, is an iron-sulfur hydrolyase that catalyzes the non-limiting interconversion of citrate and isocitrate in the tricarboxylic acid cycle. It is expressed in the mitochondria and maintains a citrate:isocitrate ratio of approximately 10:1. ACO2 contains a redox-sensitive iron-sulfur cluster that exists in two states: active (Fe4S4) and inactive (Fe3S4). ACO2 activity is dependent on the state of this cluster as well as the presence of two conserved cysteine residues. In normal prostate epithelial cells ACO2 activity is prevented due to the high levels of zinc inhibiting the enzyme. In these citrate-producing epithelial cells citrate oxidation is impaired allowing citrate to accumulate and exhibit a citrate:isocitrate ratio of approximately 30:1. In malignant prostate cells zinc is unable to accumulate, therefore ACO2 activity resumes and citrate is oxidized.
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基因ID
- 50
抗原
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