SOD1 抗体
Quick Overview for SOD1 抗体 (ABIN737346)
抗原
See all SOD1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- Cow, 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from mouse SOD1
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亚型
- IgG
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应用备注
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WB(1:100-500)
Optimal working dilution should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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: "Differential proteome and gene expression reveal response to carbon ion irradiation in pubertal mice testes." in: Toxicology letters, Vol. 225, Issue 3, pp. 433-44, (2014) (PubMed).
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: "Differential proteome and gene expression reveal response to carbon ion irradiation in pubertal mice testes." in: Toxicology letters, Vol. 225, Issue 3, pp. 433-44, (2014) (PubMed).
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- SOD1 (Superoxide Dismutase 1, Soluble (SOD1))
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别名
- SOD1
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背景
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Synonyms: Superoxide Dismutase 1, ALS 1, ALS, ALS1, Amyotrophic lateral sclerosis 1 adult, Amyotrophic lateral sclerosis 1, Cu/Zn SOD, Cu/Zn superoxide dismutase, Homodimer, Indophenoloxidase A, IPOA, Mn superoxide dismutase, SOD 1, SOD, SOD soluble, SOD1, SOD2, SODC, Soluble indophenoloxidase A, Superoxide dismutase 1, Superoxide dismutase 1 soluble, Superoxide dismutase Cu Zn, Superoxide dismutase cystolic, SODC_HUMAN, Superoxide dismutase [Cu-Zn], hSod1, Ipo1, SODC, Ipo-1, Sod-1, CuZnSOD, Cu/Zn-SOD, MGC107553, B430204E11Rik, superoxide-dimutase-1.
Background: SOD1 encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. Mutations in the copper/ zinc superoxide dismutase (SOD1) gene are associated with 15- 20 % of the familial forms of motoneuron disease. This 153 amino acid metalloenzyme is expressed in virtually all cells of all organisms above bacteria and is highly conserved across species, although some minor variations do occur. The incorporation of the mutated form of the SOD1 human gene into a transgenic mouse leads to the onset of the disease that closely resembles the human condition. These animals become weak at about 2-4 months of age and rapidly lose function, which results in death 4- 6 weeks later.
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分子量
- 17kDa
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基因ID
- 20655
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途径
- Sensory Perception of Sound, Transition Metal Ion Homeostasis
抗原
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