Recombinant Keratin 6 抗体 (C-Term)
Quick Overview for Recombinant Keratin 6 抗体 (C-Term) (ABIN7795793)
抗原
抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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原理
- Rabbit anti-Cytokeratin 6 Recombinant Monoclonal Antibody [BLR357N] - BSA-Free
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纯化方法
- Purified
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免疫原
- between 514 and 564 (C-term)
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亚型
- IgG
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anti-Keratin 6 (KRT6) antibody
KRT6 适用: 人, 小鼠, 大鼠 IF, IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Keratin 6 (KRT6) antibodyKRT6 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-606R unconjugated Recombinant Antibody
anti-Keratin 6 (KRT6) antibodyKRT6 适用: 人 WB 宿主: 小鼠 Monoclonal 4A1 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1000 μg/mL
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缓冲液
- Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2 - 8 °C
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有效期
- 12 months
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- Keratin 6 (KRT6)
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别名
- Cytokeratin 6
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背景
- Cytokeratins 5 and 6 are type II cytokeratins and consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. In normal tissue, Cyokeratin 5 is specifically expressed in the basal layer of the epidermis with family member KRT14 while Cytokeratin 6 is expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Cytokeratins 5 and 6 are often referred to together as "CK5/6", and are commonly expressed in various cancers, particularly those originating from epithelial tissues, and their presence is often used as a marker to identify squamous cell carcinomas or tumors with a basal cell-like phenotype [taken from NCBI Entrez Gene (Gene ID: < a href="https://www.ncbi.nlm.nih.gov/gene/3852" class="gene-values" target="_blank">3852 and < a href="https://www.ncbi.nlm.nih.gov/gene/3853" class="gene-values" target="_blank">3853)].
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基因ID
- 3853
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UniProt
- P02538
抗原
-
