Recombinant Neurofibromin 1 抗体 (C-Term)
Quick Overview for Recombinant Neurofibromin 1 抗体 (C-Term) (ABIN7795775)
抗原
See all Neurofibromin 1 (NF1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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原理
- Rabbit anti-Neurofibromin 1 Recombinant Monoclonal Antibody [BLR345M]
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纯化方法
- Purified
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免疫原
- between 2789 and 2839 (C-term)
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亚型
- IgG
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应用备注
- IP,20 μL/mg lysate,WB,11000,Flow-Cyt,Fixed in 4 % formaldehyde and permeabilized with 90 % methanol. 1 μL per 1 x 10^6 cells.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- Phosphate Buffered Saline (PBS) with 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2 - 8 °C
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有效期
- 12 months
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- Neurofibromin 1 (NF1)
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别名
- Neurofibromin 1
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背景
- Inactivating mutations in NF1 (neurofibromin 1) result in neurofibromatosis type I (NF1) which is characterized by Schwann cell neurofibromas, café-au-lait spots, and benign lesions of the iris. At the cellular level, NF1 functions as a negative regulator of Ras activity. Loss of NF1 leads to increased levels of active Ras-GTP which is important for the formation and maintenance of Schwann cell tumors.
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基因ID
- 4763
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UniProt
- P21359
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途径
- cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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