Recombinant ARID1A 抗体 (AA 750-800)
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Quick Overview for Recombinant ARID1A 抗体 (AA 750-800) (ABIN7795677)
抗原
See all ARID1A 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 750-800
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原理
- Rabbit anti-ARID1A/BAF250 Recombinant Monoclonal Antibody [BLR279L]
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纯化方法
- Purified
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免疫原
- Between 750 and 800
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亚型
- IgG
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应用备注
- Flow-Cyt,Fixed in 4 % formaldehyde and permeabilized with 90 % methanol. 1 μL per 1 x 10^6 cells.,ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,IP,20 μL/mg lysate ,WB,11000 (3-8 % Tris-acetate gel recommended)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 50 μg/mL
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缓冲液
- Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2 - 8 °C
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有效期
- 12 months
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- ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))
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别名
- ARID1A/BAF250
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背景
- The SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin (SMARC), also called BRG1-associated factors (BAFs), have been identified as components of the human SWI/SNF-like chromatin-remodeling protein complexes. SWI/SNF complexes possess ATPase and DNA helicase activity that promotes transcriptional activation of genes normally repressed by chromatin structure. ARID1A/BAF250 is a noncatalytic subunit that is a member of the ARID (AT-rich interactive domain-containing protein) family of DNA binding proteins. ARID1A/BAF250 has been shown to play a role in the tumor suppressor activity of the SWI/SNF complexes. ARID1A/BAF250 is required for differentiation-associated cell cycle arrest.
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基因ID
- 8289
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UniProt
- O14497
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Tube Formation
抗原
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