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Recombinant PD-1 抗体

This Human 单克隆 anti-PD-1 antibody (Clone 29F-1A12) specifically detects PD-1 in FACS. The antibody is reactive with 小鼠 samples.
产品编号 ABIN7795506
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant PD-1 抗体 (ABIN7795506)

抗原

See all PD-1 (PDCD1) 抗体
PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

抗体类型

Recombinant Antibody

适用

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小鼠

宿主

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Human

克隆类型

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单克隆

标记

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This PD-1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

29F-1A12
  • Expression System

    Mammalian cells

    原理

    Recombinant Anti-mouse PD1 Monoclonal Antibody (Clone: 29F.1A12.1), Human IgG1 Fc Silent Kappa

    产品特性

    The rat anti-mouse PD-1 monoclonal antibody 29F.1A12 (rat IgG2a kappa) reacts with the mouse PD-1 protein (programmed death-1 or CD279) encoded by the mouse Pdcd1 gene, a member of the CD28 family of the Ig superfamily. PD-1 has two ligands, PD-L1 and PD-L2, both of which belong to the B7 family. It has been shown that in mouse models of melanoma, tumor growth can be transiently arrested via treatment with the anti-mouse PD-1 and anti-mouse PD-L1 antibodies which block the interaction between the PD-L1 protein and its receptor PD-1 protein. The 29F.1A12 monoclonal antibody blocks the binding of both the mouse PD-L1 protein and the mouse PD-L2 protein to the mouse PD-1 protein. Our recombinant 29F.1A12 antibodies have a part (variable regions) or complete amino acid sequences of the rat anti-mouse PD-1 monoclonal antibody (hybridoma clone name or number: 29F.1A12).

    纯化方法

    Protein A or G affinity column

    纯度

    >95 % by reducing SDS-PAGE

    亚型

    Fc Silenced, IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    > 3 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
  • 抗原

    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

    别名

    PD1

    途径

    Cancer Immune Checkpoints
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