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HTR2A 抗体 (AA 65-160) (FITC)

This FITC-conjugated 兔 多克隆 anti-HTR2A antibody specifically detects HTR2A in WB, IF (cc) 和 IF (p). The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN737023
发货至: 中国
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Quick Overview for HTR2A 抗体 (AA 65-160) (FITC) (ABIN737023)

抗原

See all HTR2A 抗体
HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))

适用

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人, 大鼠, 小鼠

宿主

  • 74
  • 1
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克隆类型

  • 76
  • 1
多克隆

标记

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This HTR2A antibody is conjugated to FITC

应用范围

  • 55
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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 15
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    AA 65-160

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human 5-HTR2A

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))

    别名

    5-HTR2

    背景

    Synonyms: HTR2, 5-HT2A, 5-hydroxytryptamine receptor 2A, 5-HT-2, 5-HT-2A, Serotonin receptor 2A, HTR2A

    Background: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores. Affects neural activity, perception, cognition and mood. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.

    基因ID

    3356

    UniProt

    P28223

    途径

    JAK/STAT Signaling, Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process
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