HTR2A 抗体 (Extracellular, N-Term)
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Quick Overview for HTR2A 抗体 (Extracellular, N-Term) (ABIN7042875)
抗原
See all HTR2A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-52, Extracellular, N-Term
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原理
- A Rabbit Polyclonal Antibody to 5-Hydroxytryptamine Receptor 2A
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Mouse - identical, human - 9,13 amino acid residues identical
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产品特性
- Anti-5HT2A Receptor (HTR2A) (extracellular) Antibody is directed against an epitope of the rat 5-A receptor. Anti-5HT2A Receptor (HTR2A) (extracellular) Antibody (ABIN7042875, ABIN7045286 and ABIN7045287) can be used in western blot, immunohistochemistry, and live cell flow cytometry applications. The antibody recognizes an extracellular epitope and is ideal for detecting the receptor in living cells. It has been designed to recognize rat 5-hydroxytryptamine receptor 2A from rat, mouse, and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)SEASNWTIDAENR, corresponding to amino acid residues 40-52 of rat 5-Hydroxytryptamine receptor 2A
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亚型
- IgG
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anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (AA 65-160) antibody
HTR2A 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (AA 51-150) antibodyHTR2A 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (AA 296-309) antibodyVerified HTR2A 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (N-Term) antibodyHTR2A 适用: 人, Pig, Bat, 马 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (AA 385-471) antibodyHTR2A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (AA 16-30), (N-Term) antibodyHTR2A 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB52772 unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (AA 21-120) antibodyHTR2A 适用: 大鼠, 小鼠 ELISA, IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (AA 171-270) antibodyHTR2A 适用: 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (N-Term) antibodyHTR2A 适用: 人, 小鼠, Pig, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (N-Term) antibodyHTR2A 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:200
FC: 5 mg per reaction
ICC: The optimal concentration should be determined by the user
IHC: 1:1200
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7234591)
Blocking Peptide: (ABIN7234591)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))
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别名
- HTR2A
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背景
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Synonyms: 5-Hydroxytryptamine receptor 2A, Serotonin receptor 2A
Description: 5-HT is involved in a diverse array of physiological and biological processes. In the brain, 5-HT affects sleep, mood, appetite, anxiety, aggression, perception, pain, and cognition1. Signaling of 5-HT is mediated by receptors that are located on the cell membrane of neurons and most other cells in the body. The 5-HT2 family consists of three G-protein coupled receptors (GPCRs): 5-HT2A, 5-HT2B, and 5-HT2C2. They are transmembrane proteins consisting of seven membrane-spanning α-helical segments with an extracellular N-terminus and an intracellular C-terminus. The binding of 5-HT to one of its receptors is thought to elicit a conformational change that activates associated heterotrimeric G proteins and recruits other downstream signaling/scaffolding molecules, such as GPCR kinases and β-arrestins.5-HT2A receptors have been found in many regions of the human brain including the cortex, brainstem, olfactory bulb, limbic system and basal ganglia3.The 5-HT2A receptor has been implicated in many mental disorders including schizophrenia, depression, obsessive compulsive disorder (OCD), attention deficit-hyperactivity disorder (ADHD), and eating disorders such as anorexia nervosa and autism spectrum disorders4.
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基因ID
- 29595
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NCBI登录号
- NM_000621
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UniProt
- P14842
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途径
- JAK/STAT Signaling, Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process
抗原
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