SPDEF/PSE 抗体 (AA 251-335) (Biotin)
Quick Overview for SPDEF/PSE 抗体 (AA 251-335) (Biotin) (ABIN735595)
抗原
See all SPDEF/PSE (SPDEF) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 251-335
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PDEF
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亚型
- IgG
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应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- SPDEF/PSE (SPDEF) (Proximal Sequence Element 1 (SPDEF))
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别名
- PDEF/SPDEF
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背景
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Synonyms: bA375E1.3, PDEF, Prostate derived Ets factor, PROSTATE EPITHELIUM SPECIC ETS TRANSCRIPTION FACTOR, Prostate epithelium-specic Ets transcription factor, Prostate specic Ets, Prostate-derived Ets factor, Prostate-specic Ets, PSE, RP11-375E1__A.3, SAM POINTED DOMAIN CONTAINING ETS TRANSCRIPTION FACTOR, SAM pointed domain-containing Ets transcription factor, Spdef, SPDEF_HUMAN.
Background: SPDEF, also known as PDEF is an ETS transcription factor expressed in the prostate epithelial cells. It is thought to act as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter and also as a transcriptional activator for the SERPINB5 promoter. It is highly expressed in prostate carcinoma cells and is thought to be involved in the regulation of the prostate gland and/or prostate cancer development. It is also expressed in epithelial breast carcinoma.
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基因ID
- 25803
抗原
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