GCK 抗体 (AA 101-200)
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北京 101111
Quick Overview for GCK 抗体 (AA 101-200) (ABIN734558)
抗原
See all GCK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-200
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human GCK
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亚型
- IgG
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anti-Glucokinase (Hexokinase 4) (GCK) (AA 1-465) antibody
GCK 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) antibodyGCK 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4G6 unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) (AA 3-226) antibodyGCK 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) antibodyGCK 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) (AA 1-300) antibodyGCK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) antibodyGCK 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB5845 unconjugated Recombinant Antibody
anti-Glucokinase (Hexokinase 4) (GCK) (AA 1-465) antibodyGCK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) (AA 1-465) antibodyGCK 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) (AA 194-410) antibodyGCK 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) (N-Term) antibodyGCK 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Effects of a Novel Glucokinase Activator, HMS5552, on Glucose Metabolism in a Rat Model of Type 2 Diabetes Mellitus." in: Journal of diabetes research, Vol. 2017, pp. 5812607, (2017) (PubMed).
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: "Effects of a Novel Glucokinase Activator, HMS5552, on Glucose Metabolism in a Rat Model of Type 2 Diabetes Mellitus." in: Journal of diabetes research, Vol. 2017, pp. 5812607, (2017) (PubMed).
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- GCK (Glucokinase (Hexokinase 4) (GCK))
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别名
- GCK/Glucokinase
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背景
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Synonyms: GK, GLK, HK4, HHF3, HKIV, HXKP, LGLK, MODY2, FGQTL3, Glucokinase, Hexokinase type IV, HK IV, Hexokinase-4, Hexokinase-D, GCK
Background: Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the synthesis of glycogen. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage.
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基因ID
- 2645
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UniProt
- P35557
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途径
- MAPK Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process
抗原
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