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Endoglin 抗体 (FineTest®700)

This anti-Endoglin antibody is a 大鼠 单克隆 antibody detecting Endoglin in FACS. Suitable for 小鼠.
产品编号 ABIN7675479
发货至: 中国

Quick Overview for Endoglin 抗体 (FineTest®700) (ABIN7675479)

抗原

See all Endoglin (ENG) 抗体
Endoglin (ENG)

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This Endoglin antibody is conjugated to FineTest®700

应用范围

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Flow Cytometry (FACS)

克隆位点

MJ7-18
  • 原理

    FineTest®700 Anti-Mouse CD105 Antibody

    亚型

    IgG2a, kappa
  • 应用备注

    Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0. 1 % sodium azide, 1 %BSA, pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    4 °C

    储存方法

    2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    Endoglin (ENG)

    别名

    CD105

    背景

    Synonyms: END|Endoglin|Eng

    Background: CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and upregulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF-β1, TGF-β3 and modulates TGF-β signaling by interacting with TGF-β receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2, and BMP-7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging and prognosis, and has therapeutic potential for some solid tumors and other angiogenic diseases.

    分子量

    0

    基因ID

    13805

    UniProt

    Q63961
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