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CD72 抗体 (FineTest®700)

This anti-CD72 antibody is a 小鼠 单克隆 antibody detecting CD72 in FACS. Suitable for 人.
产品编号 ABIN7675253
发货至: 中国

Quick Overview for CD72 抗体 (FineTest®700) (ABIN7675253)

抗原

See all CD72 抗体
CD72 (CD72 Molecule (CD72))

适用

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宿主

  • 38
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小鼠

克隆类型

  • 39
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  • 2
单克隆

标记

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  • 1
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This CD72 antibody is conjugated to FineTest®700

应用范围

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Flow Cytometry (FACS)

克隆位点

3F3
  • 原理

    FineTest®700 Anti-Human CD72 Antibody

    亚型

    IgG2b, kappa
  • 应用备注

    Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0. 1 % sodium azide, 1 %BSA, pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    4 °C

    储存方法

    2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    CD72 (CD72 Molecule (CD72))

    别名

    CD72

    背景

    Synonyms: Lyb-2|Ly-19.2|Ly-32.2

    Background: CD72 is a 39-43 kD type II membrane glycoprotein. It is a disulfide-linked homodimer belonging to C-type lectin family. CD72 is a pan-B cell marker expressed on pre-pre-B cells throughout B cell differentiation with the exception of plasma cells. It is also expressed on follicular dendritic cells, splenic red pulp macrophages (but not on peripheral blood monocytes), and liver Kupffer cells. CD72, a negative coreceptor of B cells, contains immunoreceptor tyrosine-based inhibitory motifs in the cytoplasmic domain which has been shown to recruit the tyrosine phosphatase SHP-1. Ligation of CD72 with its ligand regulates CD72 tyrosine dephosphorylation and SHP-1 dissociation to promote B cell activation and proliferation. CD100 and CD5 have been shown to be CD72 ligands. The CD100-CD72 interaction plays a role in maintenance of B cell homeostasis.

    分子量

    0

    基因ID

    971

    UniProt

    P21854

    途径

    BCR Signaling
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