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CD46 抗体 (PE-FineTest®594)

This anti-CD46 antibody is a 小鼠 单克隆 antibody detecting CD46 in FACS. Suitable for 人.
产品编号 ABIN7675171
发货至: 中国

Quick Overview for CD46 抗体 (PE-FineTest®594) (ABIN7675171)

抗原

See all CD46 抗体
CD46

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD46 antibody is conjugated to PE-FineTest®594

应用范围

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Flow Cytometry (FACS)

克隆位点

TRA-2-10
  • 原理

    PE-FineTest®594 Anti-Human CD46 Antibody

    亚型

    IgG1, kappa
  • 应用备注

    Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

    说明

    PE-FineTest®594 is designed to be excited by the blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 620 nm (e.g., a 610/20 nm bandpass filter).

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0. 1 % sodium azide, 1 %BSA, pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    4 °C

    储存方法

    2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    CD46

    别名

    CD46

    背景

    Synonyms: Complement membrane cofactor protein|measles virus receptor|MCP

    Background: CD46 is a transmembrane protein that is known as a complement membrane cofactor protein, MCP, and measles virus receptor. It is widely expressed on leukocytes, platelets, epithelial cells, and fibroblasts. Multiple isoforms of CD46 have been reported with molecular weights ranging from 45-75 kD. CD46 binds complement components C3b and C4b and has been reported to play a role in T cell regulation. In addition to the complement components, CD46 has been shown to interact with moesin, c-Src, tetraspanin 4, c-Yes, and integrin β1. CD46 is also known to be a cellular receptor for human measles virus and human herpes virus-6 as well as other human pathogens, such as Streptococcus pyogenes. Defects in CD46 have been associated with hemolytic-uremic syndrome.

    分子量

    0

    基因ID

    4179

    UniProt

    P15529

    途径

    Regulation of Actin Filament Polymerization
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