KCC2 抗体
Quick Overview for KCC2 抗体 (ABIN7674503)
抗原
See all KCC2 (SLC12A5) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SLC12A5-Specific antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- solute carrier family 12(potassium-chloride transporter), member 5
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亚型
- IgG
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应用备注
- WB: 1:500-1:5000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- KCC2 (SLC12A5) (Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 5 (SLC12A5))
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别名
- SLC12A5
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背景
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Synonyms: Solute carrier family 12 member 5|Electroneutral potassium-chloride cotransporter 2|K-Cl cotransporter 2 (hKCC2)|Neuronal K-Cl cotransporter|SLC12A5|KCC2|KIAA1176
Background: KCC2, encoded by SLC12A5, is a neuron-specific K+-Cl-cotransporter that is essential for Cl-homeostasis and inhibitory synaptic transmission in brain. KCC2 is expressed at high levels in neurons throughout the nervous system. KCC2 deletion caused animal death. Alterations of KCC2 have been linked to neuropathic pain, temporal lobe epilepsy, and other diseases. This antibody can detect ~130 kda monomer and ~250 kDa dimer of KKC2 in brain lysate.
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分子量
- 126 kDa
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基因ID
- 57468
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UniProt
- Q9H2X9
抗原
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